And some of these side effects are more common with certain uses of Prolia. Prolia can also increase this risk. Your body needs calcium to build and maintain strong bones. Your heart, muscles and nerves also need calcium to function properly. Some studies suggest that calcium, along with vitamin D, may have benefits beyond bone health: perhaps protecting against cancer, diabetes and high blood pressure. In fact, bone breakdown is higher in the first several months after you stop Prolia. Before you receive Prolia, tell your doctor if you have kidney disease (or if you are on dialysis), a weak immune system, a history of hypoparathyroidism or thyroid surgery, a history of intestinal surgery, a condition that makes it hard for your body to absorb nutrients from food, or if you are allergic to latex. Prolia is a medicine that may affect the ability of your body to fight infections. The risk is highest in people with cancer, blood cell disorders, pre-existing dental problems, or people treated with steroids, chemotherapy, or radiation. Youll receive Prolia doses from a healthcare professional. They may also suggest exercises to help improve your bone strength and lower your risk for fractures and osteoporosis. Talk with your doctor about your health history and discuss your risks with Prolia treatment. Having dental procedures, including tooth extractions, during Prolia treatment may increase your risk of dental side effects. BMD was increased by 8.8% at the lumbar spine, 6.4% at the total hip, and 5.2% at the femoral neck in trials that measured BMD after three years of treatment with Prolia. Its important to practice good oral hygiene during Prolia treatment. There are no known interactions with Prolia and other medications, supplements, or other products. If youd like to know more about the differences and similarities of Prolia and Evenity, see this comparison. Hair loss with Prolia was reported after the drugs initial studies were done and it was approved for use. You may report side effects to FDA at 1-800-FDA-1088. Copyright 1996-2023 Cerner Multum, Inc. Available for Android and iOS devices. If youre concerned about weight gain with Prolia, talk with your doctor. For example, in the studies, people taking Prolia for up to 8 years didnt have significant side effects compared with people taking a placebo.
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